Oncology Animal Models

A microscope is connected to a computer displaying tissue samples, used for analyzing animal disease models in a research laboratory.

Oncology Animal Model Services

Pharmaron proudly provides unparalleled expertise in supporting drug discovery through cutting-edge oncology animal model services. Our team brings a wealth of experience, making us a trusted oncology CRO in the industry.

With an extensive library of over 1,700 tumor models, we ensure our clients have access to the ideal model for their specific research needs without delays. We offer many models, including xenografts and syngeneic tumor models for advanced immuno-oncology studies. Utilizing state-of-the-art imaging, immune profiling, and biomarker technologies, we deliver reproducible, reliable data that accelerates decision-making.

Our teams are at the forefront of innovation, helping our clients unveil mechanisms of drug resistance and support the discovery of cancer targets through the creation of genetically modified tumor models and in vivo CRISPR screening programs.

We know that timing is essential. Therefore, Pharmaron provides results in excellent turnaround times, including short lead times for study initiation, prompt quoting, timely updates on study progress, and access to our in-house biomarker and bioanalysis capabilities.

Study Types:

A large white X-ray machine labeled "X-RAD 225" with a warning sign and a door displaying "X-RAY ON." A digital control panel with buttons and labels is on the front. The machine, used in genetic toxicology studies, is situated in a clean, industrial environment.

Tumor Models            

  • Large cancer cell line (2,300+) and tissue bank
  • 1,200+ fully validated cell-line-derived xenograft (CDX) models
  • 110+ syngeneic tumor models with complete immune profile and SOC data
  • 350+ patient-derived xenograft (PXD) models with patient history
  • 190+ orthotopic models of more than 15 cancer types, including intracranial implantation
  • Genetically engineered tumor models
  • Drug-resistant tumor models
  • Humanized tumor models
Close-up of a circular automated device holding rows of labeled test tubes for sample processing, commonly used in oncology animal models research.

ex vivo Testing Expertise

Comprehensive ex vivo testing capabilities are part of our oncology CRO service, providing critical insights to interpret oncology animal studies.

Our capabilities include the analysis of blood, tissue, and, in many cases, other body fluids, including urine and feces.

  • Bioanalysis capabilities to quantify drug exposure
  • Biomarker and immune profiling
  • Gene and protein analysis platforms
  • Flow cytometry and cell sorting
  • Histology and IHC
  • Blood biochemistry and hematology

Learn more about Pharmaron’s Oncology and Immuno-Oncology Capabilities

Download Our in vivo Oncology Brochure
Image of a Pharmaron brochure. On the left, it reads, "Pharmaron’s Comprehensive in vivo Pharmacology Solutions," highlighting sections on "Oncology and Immuno-Oncology." On the right, it states "in vivo Oncology," alongside a button labeled "Download Service Overview." Plus, explore our Radiolabelled ADME services.

Research Case Studies

Poster on in vivo CRISPR screening for therapeutic target identification using a xenograft model, with charts, graphs, and downloadable PDF option.

in vivo CRISPR study to identify novel therapeutic cancer drug targets

An informational poster showcasing a study on X-ray radiation therapy across mouse tumor models, integrating aspects of genetic toxicology. The background has an abstract geometric pattern. The text reads "A Multifaceted Study of X-Ray Radiation Therapy Across Diverse Mouse Tumor Models" with a "Download Below" button.

A study on X-ray radiation therapy across various mouse tumor models

A promotional poster displays scientific information on leveraging imaging technologies for drug potency testing in orthotopic and heterotopic tumor models. It includes text, graphs, and images related to Preclinical ADME studies. A "Download Below" button is visible, along with Pharmaron's logo.

Leveraging IVIS imaging techniques for drug potency testing

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