Two Teams in Sync: in vitro Biology & in vivo Pharmacology
Pharmaron’s in vitro biology and in vivo pharmacology teams are integral to our drug R&D service platform. The two teams work together to advance the understanding of novel biological targets for their disease-modifying efficacy and identify potential safety liabilities in diverse areas, such as oncology, CNS, metabolic and CV diseases, and inflammation/pain. This is done by characterizing the biological effect from in vitro, ex vivo, and in vivo settings with both small and large molecule entities.
The seamless partnership between in vitro biology and in vitro pharmacology groups extends to all the in vivo programs, as the in-life studies are accompanied by timely ex vivo pharmacology/in vitro and in vivo DMPK, target engagement, and biomarkers measurements to help design and interpret the in vivo efficacy data. The tight collaboration leads to better study planning and faster issue identification/resolution, ensures accelerated program advancement, and, most importantly, provides high-quality data.
Learn more about our in vivo pharmacology services
