Poster Authors:

Christopher Wellaway, Pengwei Pan, Chunyan Han, Sebastien Campos, Gillian Watt, Fang He, Kyle Fang and Jianmin Fu

The discovery of heterobifunctional degraders follows a well-defined iterative workflow requiring intensive resources from computer-aided drug discovery, medicinal/synthetic chemistry, biology, and
DMPK. Pharmaron has developed a broad suite of tools and assays and has a team with a wealth of experience leading protein degrader projects.

In this poster, we present
1. An introduction to our protein degrader design and synthesis suite
2. Some examples of in vitro evaluation assays
3. ADME/PK evaluation examples for protein degraders