The Use of Compaction Simulation as a Tool To Aid Successful Tablet Formulation

An image of a promotional poster by Pharmaron for an event at the 13th APS PharmSci Conference in 2022. The poster, titled "The Use of Compaction Simulation as a Tool to Aid Successful Tablet Formulation," also highlights key insights into Preclinical ADME studies. A "Download Poster Below" button is displayed.

Poster Authors:

Sarah A Stewart, Indigo Lily Dean, Mark Lawlor and Simon M Lawrence

Pharmaron UK LTD, Innovation Park, Hertford Road, Hoddesdon, EN11 9FH, UK

Pharmaron presented this poster at the APS PharmSci Conference 2022 showcasing its formulation experience within drug product development. The poster shows data visualization of APIs and blends data for two of three attributes for USP <1062> Tablet Compression Characterization, namely:

  • Compactibility: ability of a powder to form a compact of specified strength when compressed -Tensile Strength vs Solid Fraction
  • Tabletability: tensile strength as a function of compaction pressure – Tensile Strength vs Compression Pressure